ICG-001 from MedChemExpress

Product Specs
ItemICG-001
CompanyMedChemExpress
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberHY-14428
Quantity10 mM * 1 mL
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.86%
TypeChemical
Molecular Weight548.63
FormulaC₃₃H₃₂N₄O₄
Research AreaCancer

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(1) Attenuation of amyloid‐β‐induced mitochondrial dysfunction by active components of anthocyanins in HT22 neuronal cellsMedComm (2020)August 1, 2023Jing Li, Pan Wang, Ming‐Jie Hou, Bao Ting Zhuwater. The ATP Assay Kit (S0026) was purchased from Beyotime Biotechnology (Shanghai, China). ICG‐001 (HY‐14428) was purchased from MedChemExpress (Monmouth Junction, NJ, USA). LF3 (S8474) was purchased from Selleck

(2) ASPP2 suppresses tumour growth and stemness characteristics in HCC by inhibiting Warburg effect via WNT /β‐catenin/ HK2 axisJournal of Cellular and Molecular MedicineMarch 1, 2023Beibei Liang, Yuan Jiang, Shaohua Song, Wei Jing, Hao Yang, Li Zhao, Ya Chen, Qiqi Tang, Xuhui Li, Lisha Zhang, et al.for 1–2 h. The detail antibodies information can be found in Table S1. XAV‐939 (HY‐15147), ICG‐001 (HY‐14428) were all purchased from MedChemExpress, 2‐DG (SIGMA, D8375), 3‐bp (S5426) was purchased from Selleck.

(3) Insulin-like growth factor 2 mRNA-binding protein 3 promotes kidney injury by regulating β-catenin signalingJCI insightJanuary 24, 2023Song D, Shang J, Long Y, Zhong M, Li L, Chen J, Xiang Y, Tan H, Zhu H, Hong X, et al.medium for various periods as indicated. In some experiments, HKC-8 cells were pretreated with ICG-001 (HY-14428; MedChemExpress) at 10 μM for 1 hours, followed by incubation with vehicle or Wnt3a for an additional

(4) Oxidative stress-triggered Wnt signaling perturbation characterizes the tipping point of lung adeno-to-squamous transdifferentiationSignal transduction and targeted therapyJanuary 11, 2023Fang Z, Han X, Chen Y, Tong X, Xue Y, Yao S, Tang S, Pan Y, Sun Y, Wang X, et al.and total RNA was extracted for real-time PCR analyses. ICG-001 was purchased from MedChemExpress (HY-14428) and diluted in Dimethyl Sulfoxide (DMSO). For ROS inducer treatment, cells were exposed to PHEN (500

(5) Aberrant androgen action in prostatic progenitor cells induces oncogenesis and tumor development through IGF1 and Wnt axesNature CommunicationsDecember 1, 2022Won Kyung Kim et al.vehicle, dimethyl sulfoxide (DMSO), antiandrogen, 10 µM Enzalutamide (Enz), Wnt inhibitors, 10 µM ICG-001 (HY-14428, MedChemExpress), 10 µM iCRT3 (HY-103705, MedChemExpress), or combination of Enz and ICG-001 or iCRT3

(6) Targeting Wnt/β-Catenin Signaling Exacerbates Ferroptosis and Increases the Efficacy of Melanoma Immunotherapy via the Regulation of MITFCellsNovember 12, 2022Wang H, Zhang H, Chen Y, Wang H, Tian Y, Yi X, Shi Q, Zhao T, Zhang B, Gao T, et al.(LiCl) (cat. E0153) were purchased from Selleck (Houston, TX, USA). RSL3 (cat. HY-100218A), ICG001 (cat. HY-14428), necrosulfonamide (cat. HY-100573), nelfinavir mesylate (cat. HY-15287A), ferrostatin-1 (cat. HY-100579),

(7) PD-L1 mediates lung fibroblast to myofibroblast transition through Smad3 and β-catenin signaling pathwaysScientific reportsFebruary 23, 2022Guo X, Sunil C, Adeyanju O, Parker A, Huang S, Ikebe M, Tucker TA, Idell S, Qian G.Center at Tyler. Small molecular inhibitors including SIS3 (HY-13013), SB230580 (HY-10256), ICG001 (HY-14428) and actinomycin D (Act D, HY-17559) were purchased from MedChemExpress (Monmouth Junction, NJ). The

(8) Trigonelline reverses high glucose-induced proliferation, fibrosis of mesangial cells via modulation of Wnt signaling pathwayDiabetology & metabolic syndromeFebruary 9, 2022Chen C, Shi Y, Ma J, Chen Z, Zhang M, Zhao Y.(100 μM), and group E was treated with the Wnt/β-catenin signaling pathway inhibitor ICG-001 (3 µM; HY-14428, MedChemExpress Co. Ltd., New Jersey, USA), group A, B, C, D, E groups were incubated in high glucose

(9) Inhibition of RIP1-RIP3-mediated necroptosis attenuates renal fibrosis via Wnt3α/β-catenin/GSK-3β signaling in unilateral ureteral obstructionPloS oneJanuary 1, 2022Piao SG, Ding J, Lin XJ, Nan QY, Xuan MY, Jiang YJ, Zheng HL, Jin JZ, Li C.MedChemExpress, USA [31]); 5) UUO+ICG-001 group, UUO rats received ICG-001 (5mg/kg intraperitoneal, HY-14428, MedChemExpress, USA [28]. The UUO model was created as previously described [11]. Rats were anesthetized

(10) Surfactant trial in Latin American infants criticisedBMJ (Clinical research ed.)March 10, 2001Charatan F.

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ICG-001 from MedChemExpress

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